Embryonic Stem Cell-Derived Cardiomyocyte Heterogeneity and the Isolation of Immature and Committed Cells for Cardiac Remodeling and Regeneration
Pluripotent stem cells represent one promising source for cell replacement therapy in heart, but differentiating read more embryonic stem cell-derived cardiomyocytes (ESC-CMs) are highly heterogeneous and show a variety of maturation states.In this study, we employed an ESC clonal line that contains a cardiac-restricted ncx1 promoter-driven puromyc